1,685 research outputs found

    Hybrid coordinate formulation used for the design of attitude control systems for flexible spacecraft

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    Formulation combines certain advantages of discrete and distributed coordinates by using both simultaneously. In report summarizing method, theoretical development is extended as necessary for applications of practical interest. Explicit analyses are presented in sufficient detail to establish utility in flexible space vehicle control system of hybrid coordinate formulation

    On the solution of the general single-stage location-allocation problem by a branch-and-bound algorithim

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    The location-allocation problem is treated from the standpoint of the computational efficiency of a mixed-integer programming formulation solved by a branch-and-bound algorithm. Previous formulations of the problem are analyzed and a new formulation is developed

    Improvements to 232-thorium, 230-thorium, and 231-protactinium analysis in seawater arising from GEOTRACES intercalibration

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    The GEOTRACES program requires the analysis of large numbers of seawater samples for ^(232)Th, ^(230)Th, and ^(231)Pa. During the GEOTRACES international intercalibration exercise, we encountered unexpected difficulties with recovery and contamination of these isotopes, ^(232)Th in particular. Experiments were carried out to identify the source of these issues, leading to a more streamlined and efficient procedure. The two particular problems that we identified and corrected were (1) frits in columns supplied by Bio-Rad Laboratories caused loss of Th during column chemistry and (2) new batches of AG1-X8 resin supplied by Bio-Rad Laboratories released more than 100 pg of ^(232)Th during elution of sample. To improve yields and blanks, we implemented a series of changes including switching to Eichrom anion exchange resin (100-200 ÎĽm mesh) and Environmental Express columns. All Th and Pa samples were analyzed on a Neptune multi-collector inductively-coupled-plasma mass spectrometer (MC-ICP-MS) using peak hopping of ^(230)Th and ^(229)Th on the central SEM, with either ^(232)Th, ^(236)U (or both) used to monitor for beam intensity. We used in-house laboratory standards to check for machine reproducibility, and the GEOTRACES intercalibration standard to check for accuracy. Over a 1-y period, the 2 s.d. reproducibility on the GEOTRACES SW STD 2010-1 was 2.5% for ^(230)Th, 1.8% for ^(232)Th, and 4% for ^(231)Pa. The lessons learned during this intercalibration process will be of value to those analyzing U-Th-Pa and rare earth elements as part of the GEOTRACES program as well as those using U-series elements in other applications that require high yields and low blanks, such as geochronology

    Disrupting Enrollment Practices For Advanced Courses: Exploring Ways To Close The Opportunity Gap For Black High School Students

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    In this research project, I use Critical Race Theory (Ladson-Billings & Tate, 1995) to investigate the central problem of why there is a disproportionately low number of Black students in advanced courses. In this qualitative study, I explored the experiences of four Black students in advanced high school courses. The purpose of my work in this dissertation was to first disrupt the current enrollment practices in high schools. Secondly, I explored ways to close the opportunity gap in advanced high school courses for Black students. The findings from my research helped inform recommendations for school leaders to close the opportunity gap at their schools. Ultimately, the actionable manifestation of my research was the development and organization of a community outreach program. The outreach event served as an opportunity for underrepresented students and their families to learn about the benefits of advanced courses and how to navigate the educational system. The design and intent of this research-based community initiative can serve as a model for other schools and communities to promote more expansive opportunities for students of color in advanced high school courses

    Synthesis of N-Acyl-N,O-Acetals from N-Aryl Amides and Acetals in the Presence of TMSOTf

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    Secondary amides undergo in situ silyl imidate formation mediated by TMSOTf and an amine base, followed by addition to acetal acceptors to provide N-acyl-N,O-acetals in good yields. An analogous, high-yielding reaction is observed with 2-mercaptothiazoline as the silyl imidate precursor. Competing reduction of the acetal to the corresponding methyl ether via transfer hydrogenation can be circumvented by the replacement of i-Pr2NEt with 2,6-lutidine under otherwise identical reaction conditions

    A New Supersymmetric CP Violating Contribution to Neutral Meson Mixing

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    We study the contribution to flavor changing neutral current processes from box diagrams with light higgsinos and squarks. Starting with just the Cabbibo Kobayashi Maskawa (CKM) phase, we find contributions to the K0K^0 and B0B^0 meson mass matrices that are out of phase with the Standard Model contributions in the case of substantial mixing between the up-type squarks. This difference in phase could be large enough to be detected at the proposed BB factories, with interesting implications for the unitarity triangle of CKM matrix elements.Comment: 1 reference added, 1 reference clarified, 2 typos corrected (QCD corrections to K meson mixing in Tables 1 and 3). To be published in Phys. Rev. D. 15 pages (Latex), 2 figures and epsfig.sty submitte

    Anticipatory nausea in cyclical vomiting

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    BACKGROUND: Cyclical Vomiting Syndrome (CVS) is characterised by discrete, unexplained episodes of intense nausea and vomiting, and mainly affects children and adolescents. Comprehending Cyclical Vomiting Syndrome requires awareness of the severity of nausea experienced by patients. As a subjective symptom, nausea is easily overlooked, yet is the most distressing symptom for patients and causes many behavioural changes during attacks. CASE PRESENTATION: This first-hand account of one patient's experience of Cyclical Vomiting Syndrome shows how severe nausea contributed to the development of anticipatory nausea and vomiting (ANV), a conditioned response frequently observed in chemotherapy patients. This conditioning apparently worsened the course of the patient's disease. Anticipatory nausea and vomiting has not previously been recognised in Cyclical Vomiting Syndrome, however predictors of its occurrence in oncology patients indicate that it could complicate many cases. CONCLUSION: We suggest a model whereby untreated severe and prolonged nausea provokes anxiety about further cyclical vomiting attacks. This anxiety facilitates conditioning, thus increasing the range of triggers in a self-perpetuating manner. Effective management of the nausea-anxiety feedback loop can reduce the likelihood of anticipatory nausea and vomiting developing in other patients
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